1. Choose the right cage: Before setting up a mouse cage, it’s important to choose an appropriate cage for your pets. Opt for a wire or plastic cage with adequate ventilation and enough space for your mice to comfortably explore and move around.

2. Clean and disinfect: Thoroughly clean and disinfect the cage using a mild detergent and warm water. Rinse well and allow the cage to air dry completely before assembling any components.

3. Place on a stable surface: Position the cage on a level, stable surface that is away from direct sunlight, drafts, and excessive noise.

4. Add bedding: Line the bottom of the cage with a layer of mouse-safe bedding material such as shredded paper, aspen shavings, or recycled-paper bedding. Avoid cedar or pine shavings, as they can be harmful to your pets.

5. Set up hiding spots: Mice are timid creatures that enjoy having places to hide when they feel threatened. Provide small hiding spots in the cage, like cardboard tubes or small wooden houses, for your mice to seek refuge.

6. Create an exercise area: To help promote physical activity and stimulate your mice’s curiosity, create an exercise area with toys like a running wheel and climbing structures.

7. Provide food dishes: Supply your mice with appropriate food by placing small ceramic or metal dishes containing high-quality rodent pellets at different locations in their cage.

8. Ensure proper hydration: Make sure to provide fresh water in a drip-style water bottle mounted on the side of their cage. Check this daily to ensure it is working properly and that there is always enough water available.

9. Implement gnawing options: Mice need something to gnaw on regularly for healthy teeth maintenance. Provide them with wooden toys or chew blocks specifically designed for rodents.

10. Introduce nesting materials: Offer nesting materials such as hay, shredded paper, or paper tissues. Your mice will use these materials to create comfy nests within their hiding spots.

11. Add in enrichment: Add accessories like tunnels, hanging toys, and ladders to keep your mice mentally stimulated and entertained in their new environment.

12. Attach a carry cage: Attach a smaller plastic carry cage to the main enclosure, so you have a secure place for your mouse while you clean the larger cage, or for an isolating chamber in case they need medical attention.

13. Monitor temperature and humidity: Ensure that the temperature and humidity levels stay within the acceptable range for mice (65-75°F and 45-60% humidity). Monitor these conditions regularly by placing a thermometer and hygrometer inside the cage.

14. Maintain cleanliness: Lastly, remember to clean the cage thoroughly at least once a week. Change the bedding material, wash all accessories, and scrub the cage walls with warm water and mild detergent. Doing so will help maintain a healthy living environment for your pet mice.