The Big Bang Theory, a beloved sitcom that ran from 2007 to 2019, was known for its quirky characters, geeky humor, and notable celebrity cameos. Amidst the show’s long run, several guest stars left an indelible mark on audiences. Here are the 12 best guest stars that appeared on The Big Bang Theory:

1.Stephen Hawking – The late theoretical physicist made several appearances on the show, engaging in humorous banter with Sheldon and leaving a memorable impression with both the characters and the fans.

2.Bill Gates – Playing himself in a brief but memorable scene, Gates surprised Leonard and Penny with his presence, allowing for a hilarious interaction filled with geeky excitement and awe.

3.Bob Newhart – As Professor Proton, Arthur Jeffries, Newhart played a former kids’ science show host and became a father figure to Sheldon. His dry wit and comedic timing earned him an Emmy for his role.

4.Stan Lee – The Marvel Comics legend’s appearance was comic gold as he encountered Sheldon without his pants, showcasing Lee’s sense of humor.

5.Mark Hamill – Best known as Luke Skywalker from Star Wars, Hamill’s appearance as himself officiating Sheldon and Amy’s wedding was a highlight of the series.

6.Leonard Nimoy – Although he never appeared on screen, Nimoy lent his voice to an action figure of his Star Trek character Spock in a dream sequence that delighted Sheldon to no end.

7.James Earl Jones – Jones played an exaggerated version of himself who befriends Sheldon for a day of adventures that includes a swing-set conversation and karaoke-singing.

8.Laurie Metcalf – As Mary Cooper, Sheldon’s devoutly religious mother, Metcalf’s recurring role offered heartwarming moments alongside comedic clashes with her son’s atheistic views.

9.Wil Wheaton – Initially Sheldon’s arch-nemesis turned friend, Wheaton played a fictionalized version of himself, often involved in episodes concerning geek culture.

10.Adam West – Appearing as himself during the 200th episode celebration, West portrayed Batman in Sheldons dream scenario comparing various actors who have played Batman over the years.

11.George Takei – Another Star Trek alumnus graced the show: Takei appeared as himself in Howard’s fantasy sequence blending humor with his iconic voice.

12.Carol Ann Susi (voice) – Voicing Mrs. Wolowitz before her untimely passing away left an impact with her distinctive off-screen yelling that became a signature part of Howard’s character throughout the series.

These stars contributed to making The Big Bang Theory not just a sitcom about science and friendships but also an intersection where pop culture legends met some of TV’s most beloved characters.